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Paper 2 · proteins and haemoglobin

A haemoglobin molecule is made up of four polypeptide subunits, two alpha chains and two beta chains, held together as a single functional unit. What level of protein structural organisation does this represent?

Model answer

quaternary structure

Also accepted: the quaternary structure, quaternary

Explanation: Quaternary structure describes a protein built from two or more separate polypeptide chains (subunits) assembled together into one functional molecule; haemoglobin's four chains held together by hydrogen bonds, ionic bonds and hydrophobic interactions is a classic example.

Derived from ZIMSEC Biology Paper 2, November 2004, Q6

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