Danho
ZIMSEC A Level · N2016

Biology Paper 2 November 2016

Questions
12
Total marks
20

Sit this paper online

Questions
12
Pass mark
8
Sit this paper

Answer every question in the printed order, get marked at the end, then see the answers.

The questions

Question 101

[1 marks]cell membrane structure
In a cell surface membrane, water-soluble (polar) substances cannot diffuse freely across the lipid bilayer. Which part of the membrane structure is mainly responsible for restricting this movement?
  1. AThe glycocalyx carbohydrate chains attached to the outer surface of the membrane
  2. BThe peripheral proteins loosely attached to the inner face of the membrane
  3. CThe hydrophilic phosphate heads, which face the aqueous cytoplasm and are thought to actively draw polar substances inward
  4. DThe hydrophobic fatty acid tails, which form a non-polar core that repels polar molecules

Question 102

[1 marks]cell membrane structure
The glycocalyx (carbohydrate chains attached to glycoproteins and glycolipids) is found only on the outer, extracellular surface of the cell surface membrane. What is the main biological reason for this restricted location?
  1. AIt anchors ribosomes to the inner surface of the membrane during protein synthesis
  2. BIt provides receptor and antigen sites that must face outward so other cells and molecules can detect them
  3. CIt increases the flexibility of the inner leaflet so cytoskeleton filaments can attach more securely to the inner membrane surface
  4. DIt regulates the opening of ion channels from inside the cytoplasm

Question 103

[1 marks]cell membrane structure
Glucose is a relatively large, polar molecule. Which feature of the cell surface membrane best explains why glucose cannot cross it by simple diffusion?
  1. ACholesterol molecules in the membrane bind directly to glucose and hold it in place
  2. BMembrane-bound enzymes break glucose down into smaller, more lipid-soluble molecules before it can reach and cross the membrane
  3. CThe hydrophobic core formed by the phospholipid fatty-acid tails repels polar molecules such as glucose
  4. DThe glycocalyx forms a physical barrier that traps glucose outside the cell

Question 104

[1 marks]cell membrane structure
In animal cells, folds in the cell surface membrane called microvilli evolved mainly to increase the ____ available for absorption and secretion.

Answer this when you sit the paper.

Question 105

[1 marks]cell membrane structure
Microvilli (folds in the cell surface membrane that increase surface area) are found in animal cells but are absent from plant cells. What is the main reason for this difference?
  1. APlant cells have an extra glycocalyx layer that stiffens the membrane surface
  2. BPlant cells have a rigid cellulose cell wall outside the membrane that prevents it from folding outward
  3. CPlant cells have a permanent central vacuole that flattens the membrane tightly against the surrounding cell wall, preventing outward folding
  4. DPlant cells contain chloroplasts that restrict how much the membrane can curve

Question 301

[1 marks]enzymes
Fig. 3.1 shows the oxygen pressure produced by catalase acting on hydrogen peroxide at pH 7 (curve P). The pressure rises rapidly at first, then becomes constant at about 175 kPa after roughly 40 seconds. What is the best explanation for this plateau?
  1. AThe enzyme catalase becomes denatured by the heat released as the reaction proceeds, which stops any further catalytic activity from occurring
  2. BOxygen gas re-dissolves back into the hydrogen peroxide solution at the same rate it is produced
  3. CThe hydrogen peroxide substrate has been used up, so the reaction rate falls even though enzyme is still present
  4. DThe falling pH of the reaction mixture inactivates the catalase enzyme

Question 302

[1 marks]enzymes
Curve Q in Fig. 3.1 shows catalase activity in the presence of added acid, producing oxygen more slowly than curve P (at pH 7). What is the biological reason acid lowers catalase's activity?
  1. AThe increased H+ ion concentration disrupts the ionic bonds maintaining the enzyme's active site shape, denaturing catalase
  2. BThe acid lowers the temperature of the reaction mixture, slowing the rate of molecular collisions
  3. CThe acid molecules temporarily occupy the active site and block hydrogen peroxide from binding, without changing the enzyme's overall shape at all
  4. DThe acid reacts directly with hydrogen peroxide, converting it into water without releasing any oxygen

Question 303

[1 marks]enzymes
During catalysis, hydrogen peroxide binds temporarily to the active site of catalase, forming a complex that exists only while the reaction takes place. What is this temporary structure called?

Answer this when you sit the paper.

Question 501

[1 marks]haemoglobin and protein structure
Which of the following is a property typical of fibrous proteins, such as collagen and keratin, that distinguishes them from globular proteins like haemoglobin?
  1. AThey are insoluble in water, forming long, parallel polypeptide chains crosslinked into fibres
  2. BThey fold into a compact, roughly spherical shape stabilised by many different types of bonds
  3. CThey are highly soluble in water because their hydrophilic groups face outward on a folded surface
  4. DThey function mainly as enzymes, each with a specific active site for a substrate

Question 502

[1 marks]haemoglobin and protein structure
In haemoglobin, the non-protein component that contains iron and is directly responsible for binding oxygen is called the ____.

Answer this when you sit the paper.

Question 503

[1 marks]haemoglobin and protein structure
A functional haemoglobin molecule is made of four polypeptide subunits, two alpha chains and two beta chains, held together as a single unit. What level of protein structural organisation does this represent?

Answer this when you sit the paper.

Question 504

[1 marks]haemoglobin and protein structure
The β chain of haemoglobin has a tertiary structure formed from eight helices folded into a precise 3-dimensional shape. Which combination of interactions is primarily responsible for maintaining this tertiary shape?
  1. APhosphodiester bonds between the terminal ends of the polypeptide chain
  2. BPeptide bonds linking the carboxyl group of one amino acid to the amino group of the next amino acid in the chain only
  3. CGlycosidic bonds between sugar residues attached along the polypeptide backbone
  4. DHydrogen bonds, ionic bonds, disulphide bonds, and hydrophobic interactions between R groups

More sittings of this paper

The answers, and why they are the answers

Sit the paper here to see which ones you got right. Danho explains every question, keeps your score, and works without a connection.